I have been having a lot of problem shooting tether with my IQ250 and my 15" MacBook Pro Retina.
The cable that I am using are Tether Tools, Tether Pro, USB 3.0. Sometimes I will use the active extension too.
The problem which comes back very often is that the connection lost during shoots. Particularly when the macbook pro is not connected to power outlets. Both the USB plug on the left and on the right of the Macbook pro have the same problem. Normally, it would work for a while and suddenly lost the connection and nothing else can be done other than resetting everything. Sometimes I even need to disconnect the battery of the IQ250 too.
The technical support from the dealer in Hong Kong is helping me a great deal but the problem is more than what they can help. People have been telling me that the voltage of the USB outlet of the Macbook Pro is not very stable particularly for tethering. I have already turned the battery charging in the IQ250 off, but the same thing happens.....Don't tell me that I can't tether shoot into my macbook pro outdoor. 80% of my jobs goes like this, and I am disappointed.